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Chemistry of Depression


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Learning About Depression > The Chemistry of Depression

Often individuals can be susceptible to depression due to physiological causes. From research we know that chemicals in the brain (neurotransmitters) can play a large role in the symptoms of depression. Psychiatric medicines can significantly help depressed people as the neurotransmitters of the brain are shifted through the use of antidepressant medications. Be willing to consult with an appropriate medical doctor if your depression has been ongoing for more than a few weeks or months..

 SSRI antidepressants. This very popular category of medicine includes Celexa, Paxil, Luvox, Zoloft, and Prozac. These agents specifically target the neurotransmitter seretonin, and they typically work with a low occurrence of side effects. In addition to stabilizing depressive moods, the SSRI’s can also diminish problems associated with anger outbursts, worry, PMS, and panic attacks.
 Wellbutrin works on the norepinephrine and dopamine in the brain. This medicine can be effective in restoring concentration, increasing energy, and restoring libido
 Effexor works on both the seretonin levels and the norepinephrine levels in the brain, and at higher doses it increases the effectiveness of dopamine. It can be particularly useful in cases of stubborn or resistant depression.
 Remeron, Desyrel, and Serzone, while each working somewhat differently from the other, can be effective in the treatment of depression accompanied by insomnia and anxiety.
 Depakote, Lithium, and Tegretol are used in the treatment of bipolar disorder which can involve mood swings, gross irritability, grandiosity, rapid speech, and racing thoughts..

It is not at all uncommon for some doctors to use medicines in combination with each other. Also, doses may vary from person to person. If your depression is acutely severe, or if it has hung on for weeks and months, or if it has prompted you to contemplate suicide, it would be wise to consult a psychiatrist or a medical doctor familiar with the use of these and other medicines.

At times I will hear of people saying that the use of antidepressants is merely a crutch and represents a lack of faith or a lack of real effort. We would certainly not assert the same thoughts with a person taking medicines targeting heart disease or diabetes, and it is insensitive to suggest anything different with the disease of depression. Yes, there are emotional and relational issues to adjust, but not independent of the physical.

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